منابع مشابه
Goodbye suxamethonium!
No drugs in anaesthesia are more problematic than suxamethonium. Yet, no drugs have survived as suxamethonium does in spite of crisis after crisis, and attempt after attempt at its replacement. For decades, suxamethonium has taught us neuromuscular pharmacology and provided us with an encyclopaedia of side effects, while benefiting millions and millions of our anaesthetised patients. With the a...
متن کاملUltrastructure of Reptilian Myoneural Junction
The description of motor end-plates by Doy~re (15) in 1840 initiated a series of light microscope investigations leading to the cytological concepts of the structure of the motor end-plate described in the papers of Ktihne (26), Tiegs (44), Couteaux (6-10), and Gutman and Young (22). The hundredfold or more higher resolution of the electron microscope (EM) clearly offers promise of distinct adv...
متن کاملPostoperative muscle pains and suxamethonium.
Two matched groups of patients with Hodgkin's disease undergoing a staging laparotomy received thiopentone, pancuronium bromide or suxamethonium 1.0 mg kg-1 (group 2) to facilitate tracheal intubation. There were no differences in the sites or degree of postoperative myalgia between the groups. It is concluded that efforts to reduce the frequency of suxamethonium muscle pains in patients having...
متن کاملMembrane Specialization at an Insect Myoneural Junction
Myoneural junctions were examined in the asynchronous basalar flight muscle of the beetle Pachnoda ephippiata. The outer surface of the postjunctional membrane exhibits an array of prominent projections spaced at approximately 200 A intervals which arise directly from the outer dense lamina of the plasma membrane and extend part way across the junctional cleft. The projections follow irregulari...
متن کاملThe classification of the myoneural blocking agents.
THE classification of myoneural blocking agents at present accepted at least in Great Britain, divides these drugs into two groups, viz. those which compete with acetylcholine and prevent its access to the muscle end plate, i.e. the competitive blockers, and those which themselves depolarize the end plate with the result that the normal depolarizer, acetylcholine, is no longer able to exert its...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1988
ISSN: 0007-0912
DOI: 10.1093/bja/61.5.642